TOXICITY STUDIES ON MUSSELS FROM SOGNDAL, NORWAY

Toxins from Adriatic blue mussels. A decade of studies*

A research program was initiated in 1990 to carefully examine the toxin profiles in mussels from the northern Adriatic Sea. Since then, a number of polyether toxins have been isolated and characterized, some of which represent new additions to the diarrhetic shellfish poisoning (DSP) class of biotoxins and seem to be peculiar to the Adriatic Sea. During our investigation of toxic Adriatic musse...

Recent evidence from epidemiological studies on methylmercury toxicity.

More than fifty years have passed since the outbreak of Minamata disease, and large-scale methylmercury poisoning due to industrial effluents or methylmercury-containing fungicide intoxication has scarcely happened in developed countries. On the other hand, widespread environmental mercury contamination has occurred in gold and mercury mining areas of developing countries. In this article, we p...

Bioactive agents from marine mussels

Studies on the intracerebral toxicity of ammonia.

Interference with cerebral energy metabolism due to excess ammonia has been postulated as a cause of hepatic encephalopathy. Furthermore, consideration of the neurologic basis of such features of hepatic encephalopathy as asterixis, decerebrate rigidity, hyperpnea, and coma suggests a malfunction of structures in the base of the brain and their cortical connections. The three major sources of i...

Studies on the Toxicity of Bile

In a recent communication by Arthur Edmunds, t it is stated that the fall of blood pressure produced by intravenous injection of bile salts is insignificant. The statement is supported by the reproduction of tracings obtained from such experiments. The one obtained after an injection of 5 cubic centimeters of a i per cent. solution of sodium glycocholate shows hardly any depression. The depress...